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World COVID-19 cases top 15M; US labs buckle amid testing surge

Some labs are taking weeks to return COVID-19 results over the border
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(The Associated Press)

Laboratories across the U.S. are buckling under a surge of coronavirus tests, creating long processing delays that experts say are actually undercutting the pandemic response.

With the U.S. tally of infections at 3.9 million Wednesday and new cases surging, the bottlenecks are creating problems for workers kept off the job while awaiting results, nursing homes struggling to keep the virus out and for the labs themselves, dealing with a crushing workload.

Some labs are taking weeks to return COVID-19 results, exacerbating fears that asymptomatic people could be spreading the virus if they don’t isolate while they wait.

“There’s been this obsession with how many tests are we doing per day” said Dr. Tom Frieden, a former director of the Centers for Disease Control and Prevention. “The question is how many tests are being done with results coming back within a day, where the individual tested is promptly isolated and their contacts are promptly warned.”

Frieden and other public health experts have called on states to publicly report testing turnaround times, calling it an essential metric to measure progress against the virus.

The testing lags in the U.S. come as the number of people confirmed to be infected globally passed a staggering 15 million on Wednesday, according to data compiled by Johns Hopkins University. The U.S. leads the world in cases as well as deaths, which stand at more than 142,000 nationwide. New York, once by far the U.S. leader in infections, has been surpassed by California, though that is partly due to robust testing in a state with more than twice the population of New York.

Guidelines issued by the CDC recommend that states lifting virus restrictions have testing turnaround time under four days. The agency is expected to soon issue new guidelines recommending against retesting COVID-19 patients to confirm they’ve recovered.

“It’s clogging up the system,” Adm. Brett Giroir, assistant health secretary, told reporters last week.

Zachrey Warner knows it all too well.

The 30-year-old restaurant server from Columbus, Ohio, was sent home from work July 5, a few days after he began experiencing fever, diarrhea, chest tightness and body aches. He went for a test five days later at the request of his employer and was told he’d have results within 72 hours.

Almost two weeks later, he’s still waiting.

Though Warner said most symptoms stopped a few days after he

was tested, he hasn’t been allowed to return to work without the result. On Tuesday, he received an email that the results still aren’t available and that he must remain quarantined through Thursday or until he gets his result.

“The story is always the same: Apparently the lab they send tests to received over 30,000 tests in a week and they’re backed up,” Warner said. “I’ve missed out on a whole pay period.”

Beyond the economic hurt the testing lags can cause, they pose major health risks too.

In Florida, as the state confirmed 9,785 new cases on Wednesday and the death toll rose to nearly 5,500, nursing homes have been under an order to test all employees every two weeks. But long delays for results have some questioning the point.

Jay Solomon, CEO of Aviva in Sarasota, a senior community with a nursing home and assisted living facility, said results were taking up to 10 days to come back.

“It’s almost like, what are we accomplishing in that time?” Solomon said. “If that person is not quarantined in that 7-10 days, are they spreading without realizing it?”

Test results that come back after two or three days are nearly worthless, many health experts say, because by then the window for tracing the persons’s contacts to prevent additional infections has essentially closed.

U.S. officials have recently called for ramping up screening to include seemingly healthy Americans who may be unknowingly spreading the disease in their communities. But Quest Diagnostics, one of the nation’s largest testing chains, said it can’t keep up with demand and most patients will face waits of a week or longer for results

Quest has urged health care providers to cut down on tests from low-priority individuals, such as those without symptoms or any contact with someone who has tested positive.

The U.S. is testing over 700,000 people per day, up from less than 100,000 in March. Trump administration officials point out that roughly half of U.S. tests are performed on rapid systems that give results in about 15 minutes or in hospitals, which typically process tests in about 24 hours. But last month, that still left some 9 million tests going through laboratories, which have been plagued by limited chemicals, machines and kits to develop COVID-19 tests.

There is no scientific consensus on the rate of testing needed to control the virus in the U.S., which has the most cases and deaths of any nation. But experts have recommended for months that the U.S. test at least 1 million to 3 million people daily to catch new cases.

Health experts assembled by the Rockefeller Foundation said last week that the U.S. should scale up to testing 30 million Americans per week by the fall, when school reopenings and flu season are expected to further exacerbate the virus’ spread. The group acknowledged that their figure will not be possible with the current laboratory-based testing system.

The National Institutes of Health has set up a “shark tank” competition to quickly identify promising rapid tests and has received more than 600 applications. The goal is to have new testing options in mass production by the fall.

Until then, the the backbone of U.S. testing remains at several hundred labs with high-capacity machines capable of processing thousands of samples per day. Many say they could be processing far more tests if not for global shortages of testing chemicals, pipettes and other lab materials.

Dr. Bobbi Pritt of the Mayo Clinic in Rochester, Minnesota, says the hospital’s machines are running at just 20% of capacity. Lab technicians run seven different COVID-19 testing formats, switching back and forth depending on the availability of supplies.

At Emory University Hospital in Atlanta, lab workers lobby testing manufacturers on a weekly basis to provide more kits, chemicals and other materials.

“There’s no planning ahead, we just do as many as we can and cross our fingers that we’ll get more,” said Dr. Colleen Kraft, who heads the hospital’s testing lab.

Matthew Perrone, Tammy Webber And Matt Sedensky, The Associated Press

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